Rat TLR6 ORF clone(NM_207604.1)

Name: Rat TLR6 ORF clone(NM_207604.1)
SKU: CDCL186481
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL186481

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Product Information

Gene Information

Cat. No.	CDCL186481
Description	ORF Clone of Rattus norvegicus toll-like receptor 6 DNA.
Product Type	ORF clone
Gene Abbr	TLR6
Species	Rat
ORF Size	2421bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

TLR6

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]

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