Rat TLR10 ORF clone(NM_001146035.1)

Name: Rat TLR10 ORF clone(NM_001146035.1)
SKU: CDCL186469
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL186469

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Product Information

Gene Information

Cat. No.	CDCL186469
Description	ORF Clone of Rattus norvegicus toll-like receptor 10 DNA.
Product Type	ORF clone
Gene Abbr	TLR10
Species	Rat
ORF Size	2435bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

TLR10

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

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