Rat Snx13 cDNA Clone(NM_001108708.1)

Name: Rat Snx13 cDNA Clone(NM_001108708.1)
SKU: CDFR008296
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR008296

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Product Information

Gene Information

Cat. No.	CDFR008296
Description	NativeORF clone of Rattus norvegicus sorting nexin 13 (Snx13) as transfection-ready DNA NM_001108708.1
Product Type	cDAN Clone
Gene Abbr	Snx13
Species	Rat
Vector	pCMV6Entry

Target Gene

SNX13

Background

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]

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