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Mouse Snx13 ORF Clone(NM_001014973.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR231238

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Product Information

Gene Information

Cat. No. CDCR231238
Product Type ORF Clone
Gene Abbr Snx13
Species Mouse
Tag C-terminal TurboGFP
ORF Size 2873 bp
Size 10 ug
Vector pCMV6-AC-GFP
Target Gene SNX13
Background This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]
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