Rat Smarca4 cDNA Clone(NM_134368.1)

Name: Rat Smarca4 cDNA Clone(NM_134368.1)
SKU: CDFR014163
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014163

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Product Information

Gene Information

Cat. No.	CDFR014163
Description	NativeORF clone of Rattus norvegicus SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4) as transfection-ready DNA NM_134368.1
Product Type	cDAN Clone
Gene Abbr	Smarca4
Species	Rat

Target Gene

SMARCA4

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

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