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Rat Slc6a5 cDNA Clone(NM_203334.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR015310

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Gene Information

Cat. No. CDFR015310
Description NativeORF clone of Rattus norvegicus solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Slc6a5) as transfection-ready DNA NM_203334.1
Product Type cDAN Clone
Gene Abbr Slc6a5
Species Rat
Vector pCMV6Entry
Target Gene SLC6A5
Background This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
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