Transfected Stable Cell Lines
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Cat. No. : CDFR015310
| Cat. No. | CDFR015310 |
| Description | NativeORF clone of Rattus norvegicus solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Slc6a5) as transfection-ready DNA NM_203334.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Slc6a5 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | SLC6A5 |
| Background | This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
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