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Rat Slc6a5 ORF Clone(NM_203334.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR382386

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Product Information

Gene Information

Cat. No. CDCR382386
Product Type ORF Clone
Gene Abbr Slc6a5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2400 bp
Vector pCMV6-Entry
Target Gene SLC6A5
Background This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
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