Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR005415
| Cat. No. | CDFR005415 |
| Description | NativeORF clone of Rattus norvegicus SIVA1, apoptosis-inducing factor (Siva1) as transfection-ready DNA NM_001100982.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Siva1 |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | SIVA1 |
| Background | This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018] |
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