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Mouse Siva1 cDNA Clone(NM_001161737.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG020067

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Product Information

Gene Information

Cat. No. CDFG020067
Product Type cDNA clone
Gene Abbr Siva1
Species Mouse
ORF Size 333bp
Size 10 ug
Vector pCMV6Entry
Target Gene SIVA1
Background This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018]
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