Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR007832
| Cat. No. | CDFR007832 |
| Description | NativeORF clone of Rattus norvegicus SET domain containing 2 (Setd2) as transfection-ready DNA NM_001108189.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Setd2 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | SETD2 |
| Background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008] |
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