Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR234821
| Cat. No. | CDCR234821 |
| Product Type | ORF Clone |
| Gene Abbr | Setd2 |
| Species | Mouse |
| Tag | C-terminal TurboGFP |
| ORF Size | 7614 bp |
| Size | 10 ug |
| Vector | pCMV6-AC-GFP |
| Target Gene | SETD2 |
| Background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008] |
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