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Rat Rnf216 cDNA Clone(NM_001107122.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006827

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Gene Information

Cat. No. CDFR006827
Description NativeORF clone of Rattus norvegicus ring finger protein 216 (Rnf216) as transfection-ready DNA NM_001107122.1
Product Type cDAN Clone
Gene Abbr Rnf216
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RNF216
Background This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
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