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Mouse Rnf216 cDNA Clone(NM_207110.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL011611

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Product Information

Gene Information

Cat. No. CDFL011611
Product Type cDNA clone
Gene Abbr Rnf216
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene RNF216
Background This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
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