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Rat Rad18 cDNA Clone(NM_001077673.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005008

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Gene Information

Cat. No. CDFR005008
Description NativeORF clone of Rattus norvegicus RAD18 homolog (S. cerevisiae) (Rad18) as transfection-ready DNA NM_001077673.1
Product Type cDAN Clone
Gene Abbr Rad18
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RAD18
Background The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
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