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Mouse Rad18 cDNA Clone(NM_021385.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL011204

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Product Information

Gene Information

Cat. No. CDFL011204
Product Type cDNA clone
Gene Abbr Rad18
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene RAD18
Background The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
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