Rat Ptpn2 cDNA Clone(NM_053990.1)

Name: Rat Ptpn2 cDNA Clone(NM_053990.1)
SKU: CDFR013693
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013693

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Product Information

Gene Information

Cat. No.	CDFR013693
Description	NativeORF clone of Rattus norvegicus protein tyrosine phosphatase, non-receptor type 2 (Ptpn2) as transfection-ready DNA NM_053990.1
Product Type	cDAN Clone
Gene Abbr	Ptpn2
Species	Rat
Vector	pCMV6Entry

Target Gene

PTPN2

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]

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