Mouse Ptpn2 Insect Cell Lysate

Name: Mouse Ptpn2 Insect Cell Lysate
SKU: CLOE-2454
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2454 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2454
Introduction	This cell lysate over-expresses mouse Ptpn2 (Q06180-1) (Ser 2-Asn 314) fused with N-terminal his tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Ptpn2
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

PTPN2

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]

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