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Rat Ppargc1a cDNA Clone(NM_031347.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012652

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Gene Information

Cat. No. CDFR012652
Description NativeORF clone of Rattus norvegicus peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (Ppargc1a) as transfection-ready DNA NM_031347.1
Product Type cDAN Clone
Gene Abbr Ppargc1a
Species Rat
Vector pCMV6Entry
Target Gene PPARGC1A
Background The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
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