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Panoply™ Human PPARGC1A Knockdown Stable Cell Line

Cat.No.
CSC-DC012173
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PPARGC1A
Synonyms
LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)
Gene Description
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Gene ID
UniProt ID
Q9UBK2
mRNA Refseq
Protein Refseq
Chromosome Location
4p15.1
Function
DNA binding; RNA binding; RNA polymerase II transcription cofactor activity; androgen receptor binding; chromatin DNA binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nucleotide binding; protein binding; transcription coactivator activity; transcription factor binding;
Pathway
ATF-2 transcription factor network, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem;
MIM

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