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Rat Pparg ORF Clone(NM_001145366.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377383

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Gene Information

Cat. No. CDCR377383
Product Type ORF Clone
Gene Abbr Pparg
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1428 bp
Vector pCMV6-Entry
Target Gene PPARG
Background This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
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