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Rat Ppard ORF Clone(NM_013141.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377986

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Product Information

Gene Information

Cat. No. CDCR377986
Product Type ORF Clone
Gene Abbr Ppard
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1323 bp
Vector pCMV6-Entry
Target Gene PPARD
Background This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]
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