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Rat Plod1 ORF Clone(NM_053827.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380596

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Product Information

Gene Information

Cat. No. CDCR380596
Product Type ORF Clone
Gene Abbr Plod1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2187 bp
Vector pCMV6-Entry
Target Gene PLOD1
Background Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
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