Mouse PLOD1 ORF clone(NM_011122.3)

Name: Mouse PLOD1 ORF clone(NM_011122.3)
SKU: CDCG003358
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCG003358

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Product Information

Gene Information

Cat. No.	CDCG003358
Product Type	ORF clone
Gene Abbr	PLOD1
Species	Mouse
Host Cell	Bacterial
Source	Bacteria
ORF Size	3268bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mPlod1 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

PLOD1

Background

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

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