Rat Plat cDNA Clone(NM_013151.2)

Name: Rat Plat cDNA Clone(NM_013151.2)
SKU: CDFR010948
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010948

Inquire for Price

Product Information

Gene Information

Cat. No.	CDFR010948
Description	NativeORF clone of Rattus norvegicus plasminogen activator, tissue (Plat) as transfection-ready DNA NM_013151.2
Product Type	cDAN Clone
Gene Abbr	Plat
Species	Rat
Vector	pCMV6Entry

Target Gene

PLAT

Background

This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *