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Rat Pkm ORF Clone(NM_053297.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380104

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Product Information

Gene Information

Cat. No. CDCR380104
Product Type ORF Clone
Gene Abbr Pkm
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1596 bp
Vector pCMV6-Entry
Target Gene PKM
Background This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
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