Mouse Pkm Insect Cell Lysate

Name: Mouse Pkm Insect Cell Lysate
SKU: CLOE-2283
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2283 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2283
Introduction	This cell lysate over-expresses mouse Pkm (NP_001240812.1) (Pro2-Pro531) fused with N-terminal his tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Pkm
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

PKM

Background

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

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