Rat Pfkfb2 cDNA Clone(NM_080477.3)

Name: Rat Pfkfb2 cDNA Clone(NM_080477.3)
SKU: CDFR013468
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013468

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Product Information

Gene Information

Cat. No.	CDFR013468
Description	NativeORF clone of Rattus norvegicus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2), transcript variant 3 as transfection-ready DNA NM_080477.3
Product Type	cDAN Clone
Gene Abbr	Pfkfb2
Species	Rat
Vector	pCMV6Entry

Target Gene

PFKFB2

Background

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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