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Rat Pfkfb2 cDNA Clone(NM_001033965.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004308

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Gene Information

Cat. No. CDFR004308
Description NativeORF clone of Rattus norvegicus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2), transcript variant 1 as transfection-ready DNA NM_001033965.1
Product Type cDAN Clone
Gene Abbr Pfkfb2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PFKFB2
Background The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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