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Rat Pdk1 cDNA Clone(NM_053826.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013563

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Gene Information

Cat. No. CDFR013563
Description NativeORF clone of Rattus norvegicus pyruvate dehydrogenase kinase, isozyme 1 (Pdk1), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_053826.2
Product Type cDAN Clone
Gene Abbr Pdk1
Species Rat
Vector pCMV6Entry
Target Gene PDK1
Background Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
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