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Rat Pam ORF Clone(NM_013000.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377884

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Gene Information

Cat. No. CDCR377884
Product Type ORF Clone
Gene Abbr Pam
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2931 bp
Vector pCMV6-Entry
Target Gene PAM
Background This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
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