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Rat Pak6 cDNA Clone(NM_001106498.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006231

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Gene Information

Cat. No. CDFR006231
Description NativeORF clone of Rattus norvegicus p21 (CDKN1A)-activated kinase 6 (Pak6) as transfection-ready DNA NM_001106498.1
Product Type cDAN Clone
Gene Abbr Pak6
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PAK6
Background This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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