Mouse Pak6 ORF clone (NM_001033254.3)

Name: Mouse Pak6 ORF clone (NM_001033254.3)
SKU: CDCL145661
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL145661

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Product Information

Gene Information

Cat. No.	CDCL145661
Description	Mus musculus p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Pak6
Species	Mouse
ORF Size	2049bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

PAK6

Background

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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