Rat Pafah1b1 cDNA Clone(NM_031763.3)

Name: Rat Pafah1b1 cDNA Clone(NM_031763.3)
SKU: CDFR012895
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012895

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Product Information

Gene Information

Cat. No.	CDFR012895
Description	NativeORF clone of Rattus norvegicus platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (Pafah1b1) as transfection-ready DNA NM_031763.3
Product Type	cDAN Clone
Gene Abbr	Pafah1b1
Species	Rat
Vector	pCMV6Entry

Target Gene

PAFAH1B1

Background

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]

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