Panoply™ Human PAFAH1B1 Knockdown Stable Cell Line

Name: Panoply™ Human PAFAH1B1 Knockdown Stable Cell Line
SKU: CSC-DC011244
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC011244

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC011244
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PAFAH1B1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) [ Homo sapiens ]
Gene Symbol	PAFAH1B1
Synonyms	MDS; LIS1; LIS2; MDCR; PAFAH
Gene Description	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
GeneID	5048
Uni ProtID	P43034
mRNA Refseq	NM_000430.3
Protein Refseq	NP_000421.1
Chromosome Location	17p13.3
Function	dynactin binding; dynein binding; dynein intermediate chain binding; heparin binding; microtubule binding; phospholipase binding; phosphoprotein binding; protein binding; protein homodimerization activity;
Pathway	Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; DNA Replication, organism-specific biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; G2/M Transition, organism-specific biosystem;
MIM	601545

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