Rat PTPRM ORF clone(NM_001168632.1)

Name: Rat PTPRM ORF clone(NM_001168632.1)
SKU: CDCH395922
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH395922

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Product Information

Gene Information

Cat. No.	CDCH395922
Product Type	ORF clone
Gene Abbr	PTPRM
Species	Rat
Host Cell	Bacterial
Source	Bacterial
ORF Size	5290bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-rPtprm ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

PTPRM

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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