Mouse Ptprm cDNA Clone(NM_008984.2)

Name: Mouse Ptprm cDNA Clone(NM_008984.2)
SKU: CDFL011063
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFL011063

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Product Information

Gene Information

Cat. No.	CDFL011063
Product Type	cDNA clone
Gene Abbr	Ptprm
Species	Mouse
Size	10 ug
Vector	pCMV6Entry

Target Gene

PTPRM

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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