Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010947
| Cat. No. | CDFR010947 |
| Description | NativeORF clone of Rattus norvegicus neuronal cell adhesion molecule (Nrcam) as transfection-ready DNA NM_013150.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Nrcam |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | NRCAM |
| Background | Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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