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Rat Ng23 cDNA Clone(NM_001004069.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001273

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Gene Information

Cat. No. CDFR001273
Description NativeORF clone of Rattus norvegicus Ng23 protein (Ng23) as transfection-ready DNA NM_001004069.2
Product Type cDAN Clone
Gene Abbr Ng23
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MSH5
Background This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
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