Rat Nf2 cDNA Clone(NM_013193.1)

Name: Rat Nf2 cDNA Clone(NM_013193.1)
SKU: CDFR010978
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010978

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Product Information

Gene Information

Cat. No.	CDFR010978
Description	NativeORF clone of Rattus norvegicus neurofibromin 2 (merlin) (Nf2) as transfection-ready DNA NM_013193.1
Product Type	cDAN Clone
Gene Abbr	Nf2
Species	Rat
Vector	pCMV6Entry

Target Gene

NF2

Background

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein's function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. [provided by RefSeq, May 2022]

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