Rat Ndufs1 cDNA Clone(NM_001005550.1)

Name: Rat Ndufs1 cDNA Clone(NM_001005550.1)
SKU: CDFR001472
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001472

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Product Information

Gene Information

Cat. No.	CDFR001472
Description	NativeORF clone of Rattus norvegicus NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Ndufs1), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001005550.1
Product Type	cDAN Clone
Gene Abbr	Ndufs1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

NDUFS1

Background

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

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