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Rat Ndufs1 ORF Clone(NM_001005550.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR368533

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Product Information

Gene Information

Cat. No. CDCR368533
Product Type ORF Clone
Gene Abbr Ndufs1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2184 bp
Vector pCMV6-Entry
Target Gene NDUFS1
Background The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
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