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Rat Nbr1 cDNA Clone(NM_001024765.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003668

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Gene Information

Cat. No. CDFR003668
Description NativeORF clone of Rattus norvegicus neighbor of Brca1 gene 1 (Nbr1) as transfection-ready DNA NM_001024765.1
Product Type cDAN Clone
Gene Abbr Nbr1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene NBR1
Background The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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