Transfected Stable Cell Lines
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Cat. No. : CDFR003668
| Cat. No. | CDFR003668 |
| Description | NativeORF clone of Rattus norvegicus neighbor of Brca1 gene 1 (Nbr1) as transfection-ready DNA NM_001024765.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Nbr1 |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | NBR1 |
| Background | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
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