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Mouse NBR1 ORF clone(NM_001252223.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCH391430

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Product Information

Gene Information

Cat. No. CDCH391430
Product Type ORF clone
Gene Abbr NBR1
Species Mouse
Host Cell Bacterial
Source Bacterial
ORF Size 4576bp
Size 1ug
Format Clear Liquid
Vector pORF
Buffer 10mM Tris-HCI, 1mM EDTA, pH8.0
Warning pORF-mNbr1 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage 1 year when stored at -20°C or lower in a non-frost free freezer.
Target Gene NBR1
Background The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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