Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCH391430
| Cat. No. | CDCH391430 |
| Product Type | ORF clone |
| Gene Abbr | NBR1 |
| Species | Mouse |
| Host Cell | Bacterial |
| Source | Bacterial |
| ORF Size | 4576bp |
| Size | 1ug |
| Format | Clear Liquid |
| Vector | pORF |
| Buffer | 10mM Tris-HCI, 1mM EDTA, pH8.0 |
| Warning | pORF-mNbr1 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. |
| Storage | 1 year when stored at -20°C or lower in a non-frost free freezer. |
| Target Gene | NBR1 |
| Background | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
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