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Rat Mstn cDNA Clone(NM_019151.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011449

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Gene Information

Cat. No. CDFR011449
Description NativeORF clone of Rattus norvegicus myostatin (Mstn) as transfection-ready DNA NM_019151.1
Product Type cDAN Clone
Gene Abbr Mstn
Species Rat
Vector pCMV6Entry
Target Gene MSTN
Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
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