Rat Mbtps1 cDNA Clone(NM_053569.1)

Name: Rat Mbtps1 cDNA Clone(NM_053569.1)
SKU: CDFR013292
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013292

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Product Information

Gene Information

Cat. No.	CDFR013292
Description	NativeORF clone of Rattus norvegicus membrane-bound transcription factor peptidase, site 1 (Mbtps1) as transfection-ready DNA NM_053569.1
Product Type	cDAN Clone
Gene Abbr	Mbtps1
Species	Rat
Vector	pCMV6Entry

Target Gene

MBTPS1

Background

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

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