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Rat Map3k12 cDNA Clone(NM_013055.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010859

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Gene Information

Cat. No. CDFR010859
Description NativeORF clone of Rattus norvegicus mitogen activated protein kinase kinase kinase 12 (Map3k12) as transfection-ready DNA NM_013055.1
Product Type cDAN Clone
Gene Abbr Map3k12
Species Rat
Vector pCMV6Entry
Target Gene MAP3K12
Background This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]
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