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Mouse Map3k12 ORF Clone(NM_009582.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR247513

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Gene Information

Cat. No. CDCR247513
Product Type ORF Clone
Gene Abbr Map3k12
Species Mouse
Tag C-terminal TurboGFP
ORF Size 2666 bp
Size 10 ug
Vector pCMV6-AC-GFP
Target Gene MAP3K12
Background This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]
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