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Rat Mal cDNA Clone(NM_012798.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010600

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Gene Information

Cat. No. CDFR010600
Description NativeORF clone of Rattus norvegicus mal, T-cell differentiation protein (Mal) as transfection-ready DNA NM_012798.1
Product Type cDAN Clone
Gene Abbr Mal
Species Rat
Vector pCMV6Entry
Target Gene MAL
Background The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
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