Panoply™ Human TIRAP Knockdown Stable Cell Line

Name: Panoply™ Human TIRAP Knockdown Stable Cell Line
SKU: CSC-DC015978
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015978

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015978
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TIRAP
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein [ Homo sapiens ]
Gene Symbol	TIRAP
Synonyms	Mal; wyatt; BACTS1
Gene Description	toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Gene ID	114609
Uni Prot ID	P58753
m RNA Refseq	NM_148910.2
Protein Refseq	NP_683708.1
Chromosome Location	11q24.2
Function	Toll-like receptor 2 binding; Toll-like receptor 4 binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; protein binding, bridging; protein heterodimerization activity; protein homodimerization activity; protein kinase C binding;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Hepatitis B, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88:Mal cascade initiated on plasma membrane, organism-specific biosystem; NF-kappa B signaling pathway, organism-specific biosystem; Pertussis, organism-specific biosystem;
MIM	606252

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