Rat MAPK1 ORF clone(NM_053842.1)

Name: Rat MAPK1 ORF clone(NM_053842.1)
SKU: CDCH388640
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH388640

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Product Information

Gene Information

Cat. No.	CDCH388640
Product Type	ORF clone
Gene Abbr	MAPK1
Species	Rat
Host Cell	Bacterial
Source	Bacterial
ORF Size	1467bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-rMapk1 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

MAPK1

Background

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

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